Using a combination of 2 different vaccines against COVID-19
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(binhthuan.gov.vn) The Ministry of Health has just recommended that in case of force majeure, the second dose can be administered with the COVID-19 vaccine manufactured by Pfizer or Moderna. If it is injected the first dose with Moderna, the second dose can be given with Pfizer and vice versa.

On the evening of 08/9/2021, the Ministry of Health said that stemming from the actual situation, the need to use COVID-19 vaccine aimed at increasing coverage, early and on-time injection to prevent and control the epidemic, on 08/9, the Ministry of Health's Expert Advisory Council on Vaccine Use has met and made recommendations in case of force majeure, if the supply of vaccine is not enough to inject the second dose, the other vaccine can be used. Specifically: If the first dose is injected with a vaccine manufactured by AstraZeneca, the second dose can be given with a vaccine manufactured by Pfizer or Moderna, if the first dose with a vaccine manufactured by Moderna, the second dose can be given with a vaccine manufactured by Pfizer.

Currently, Vietnam has 05 vaccines against COVID-19 being deployed, including: AstraZeneca; Sputnik V; Pfizer; Moderna and Sinopharm. These vaccine manufacturers recommend getting full of two doses.

The ideal interval between two injections of vaccines is different. Specifically: AstraZeneca, 8-12 weeks. Sputnik V, 3 weeks after the first dose. Pfizer, 3 weeks after the first dose. Sinopharm, 3 to 4 weeks. Moderna, 28 days.

Up to now, Vietnam has received many vaccines produced by different technologies such as vector technology (manufactured by AstraZeneca, or Sputnik V), mRNA technology (produced by Pfizer, Moderna), inactivation technology (vaccine produced by Sinopharm). At the same time, the manufacturers are currently researching and developing a number of vaccines using different technologies.

Recently, due to the general shortage of vaccines, many countries have researched and used injection courses combining two vaccines with the same or different production technology, based on the type of vaccine available at each time, such as injecting vector vaccines with mRNA vaccines, or injecting 2 mRNA vaccines from different manufacturers...

The experts said that in the current global shortage of vaccines, the injection that is slower than the manufacturer's recommendation on interval of 2 injections, does not affect the protective efficacy of the vaccine./.

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